Synthesis of Novel 4-Functionalised Oxazolidin-2-ones

Abstract

The synthesis of O-substituted and O-unsubstituted 3-hydroxy-4-thioxo-oxazolidin-2-ones, functionalised 4-imino-oxazolidine-2-ones and 4-phenoxy-imino-oxazolidin-2-one starting from O-substituted and O-unsubstituted 3-hydroxy-4-imino-oxazolidin-2-ones is described. A one-pot protocol for the preparation of 4-methoxyimino-, 4-aralkoxyimino- and 4-phenoxyimino-oxazolidin-2-ones has been developed.

Key words

heterocycles - oxazolidin-2-ones - Dimroth rearrangement - thionation - ring closure

References

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